Statins and statistics

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I started with mild hypertension in my late 40s. Raised cholesterol so eventually consultant advising statins that my GP didn't want to prescribe as they "have horrible side effects". So low dose Simvastatin, then house move , new GP and dose trebled. I was running a walking group and would think nothing of a 15 mile walk aged 59. Then within weeks totally done for on a 4 mile walk, GP seeing me limp said knee replacement needed., statins "perfectly safe" Ended up on 8 Tramadol a day and had tinnitus. Quit statins and realised the knee pain was just a muscle side effect from statins, no op and no more painkillers needed. Soon able to walk 10 -12 miles again, bp down to normal, great health with more careful eating Now what is the most important muscle in your body---- your heart! Strange that he orthopaedic and ENT consultants didn't consider statin toxicity,
 
Fortunately I get no side effects from my prescription drugs. :)

Atorvastatin
Aspirin
Metformin
Gliclazide
Linagliptin
Dapagliflozin
Levothyroxine
Omeprazole
Meloxicam
Allopurinol
Tamsulosin
Lisinopril
Amlopidine
Codeine
Pregabalin
Pioglitazone.
You missed off Naproxen ...
Sorry Phil :)

To Jacob's question, I take amlodipine and atorvastatin daily after being bussed into A&E with high BP. I have many aches and pains these days but it never occurred to me to associate them with these drugs. They are just a result of ageing, genetics and not putting enough time into exercise.

I don't honestly know if they work. My BP is still a bit higher than ideal so I'm trying to improve my diet and lose weight as I think those will make a real difference. I'm getting no side effects that I can tell from the drugs so I'll keep taking them in case they are helping. That probably makes me a very typical user.
 
After five years managing borderline type-2 diabetes with diet and exercise I was put on metformin last summer by a new diabetic nurse at my clinic. I was one of the very few unlucky people who have a severe allergic reaction to it, suffered severe dehydration and ended up in the ICU with total kidney failure. My blood chemistry went completely out of whack with a potentially fatally high level of potassium. For 48hrs it was touch and go but thanks to the dedication of the nurses and doctors in the ICU I pulled through and am now fully recovered.

I was in hospital for three weeks, during which time they stopped my regular prescribed medication - atorvastatin and candesartin (for hypertension). I have been on those two for several years and never really got over the side effects they gave me, tiredness and dizziness in the morning. Tests during my stay in the hospital, while off the medication, showed slightly elevated blood pressure and cholesterol, but not to what were considered dangerous levels. I was prescribed a bunch of new meds to help with my recovery but was advised to remain off atorvastatin and candesartin until a follow-up examination in three months.

The meds prescribed for the kidney failure recovery tailed off after a couple of months and for four weeks I was completely medication free. And felt really good - strong and healthy.

At the three month follow-up (bloods submitted a week before), the renal consultant declared me fit and well. Kidney function has returned to around 70% which is fine for a 73-year old. He did however notice slightly elevated levels of cholesterol and blood pressure and put me back on the atorvastatin and candesartin. After just a couple of days I started to get my old symptoms of tiredness and dizziness back. So after a week I threw them in the bin and resolved to take my chances and go med-free. (Apart from the viagra 😉).

Eight months later, I feel great. I monitor my borderline type-2 diabetes and blood pressure, which are a bit high, bit hey, I'm an old geezer, I can't expect to have the body of a 25-year old. I'll take my chances, do deep breathing excercises for my hypertension, take plenty of exercise, eat a sensible balanced diet, and enjoy a glass of wine or a pint a few times a week. From fourteen and a half stone when I went on the metformin, I am down to twelve and a half. (I'm 5'11"). A good weight.

That's my story. I'm not advocating that people suddenly stop their meds and I might drop dead tomorrow. People do at my age (two friends in the last three months). But I do believe that pharmaceuticals are over-prescribed now, particularly when GPs are overworked and pills are the easy way out. I got a bodily Ctrl-Alt-Del reset when I nearly died last year (one consultant called it that). Just wanted to share my experience. Thanks for reading if you got this far.

Edit: Oh, and God bless the late Dr Michael Mosley whose books and TV programmes about healthy living were a huge help to my wellness.
 
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I've been on atorvastatin for about 15 years. I stopped taking it for a while a long time ago, because I had aches and pains.
Next time I had a blood test, my GP said my cholesterol was up, and wanted to increase the dose, I told him I'd stopped taking it. He asked me if the aches and pains had gone away, I had to admit they hadn't. I've been taking it ever since. I'm not saying it's all psychosomatic, but I think as one gets older, aches and pains manifest themselves, we look on the internet and blame the statins.
+1
Tried removing statins but no difference to aches and pains and cholesterol increased. I have hypertension (runs in the family) which was first diagnosed at 52 when I was still med free.
 
Jacob have a word with Brian I seem to remember he went through a few types of statins before he found one that suited him, he had a lot of problems including joint pains
Personally I’m on Atorvastatin, for me it was a no brainer with the family history of heart disease
 
Like many I am on a wide range of meds for various accumulated problems. It includes a few which are preventative rather than specific.

I was convinced that taking unnecessary meds was a slippery slope towards over reliance and potential side effect conflicts. So I tried to have an intelligent conversation with my GP about quantifying the real risks of a new preventative.

I appreciate he was probably busy but is was not a constructive conversation - "my advice is to take them". As they seem to have no side effects and may be doing good I take them.

In many cases the risk avoided is both small and statistical. An annual prescription for Atorvastin is (depending on dose) ~£25-40. The cost of hospital treatment for an additional heart attack or stroke case could be many £1000s.

For the NHS as a whole it makes good sense to prescribe cheap drugs to minimise costs. For an individual the benefit is likely very small - although adding quality of life considerations to the decision alters perspectives.
 
I think the question is who is not on statins ?

The people who are not on statins might need to be the ones to worry. To be on statins you have probably been diagnosed with some condition and are therefore on the radar, for many they are as one consultant said just ticking time bombs and might have some condition that they are not aware of that could easily be treated at an early stage before they need 999.

This does highlight a problem with the NHS in that it is reactive more than pro active and if they had the means to give everyone an MOT every say four years then they could probably catch a lot of potential conditions before they become major problems and more difficult to deal with.

Here is an idea, why don't they put some form of statin or similar into junk food to counteract it's impact on peoples health.
 
@Terry - Somerset I agree however it is the human nature to not evaluate risks correctly so we can easily make poor choices without perhaps understanding the potential risk or outcome.
A good example is my recent consultation with a cardiac Prof - he said my overall risk/load for AF is 0.6% in the last 12 months however that stat comprised two protracted events on two consecutive days where my resting heart rate was 183bpm and in AF - and on that occasion it took 6h of IV drugs at A&E to control it.
As the emergency call handler said to me when I asked if an ambulance was really necessary - 'your heart is just a muscle, at some point it'll get tired.....'
 
i was put on statins in 2010 - and after 3 days could hardly get out of car , loads of aches and pains, then they tried a different one and that had the same side effects

changed to
10mg Ezetrol - 1 in morning
400mg Bezalip - 1 in evening
and cholesterol under control for last 14+ years
 
Seems to me that the general medical advice is good but the individual has to make a judgement over apparent side effects as it may be beyond the scope of your doctor to prove a causal relationship.
So no more statins for me and will see how it goes.
 
I have been type 2 for 20+ years and have been on statins and they wanted me to take more to get a little lower but I have refused and recently have been chatting to a Diabetic nurse and she advised me to try Cinnamon powder and Cumin powder to help lower BS levels and Cholesterol, so starting to try it this weekend, we will see how it goes.
 
Been on Artovastatin for a number of years - don't recall when - after some chest pains when trying to hurry back to my car - having lost keys - to find I'd left them in the car door... possibly 2006~7? Was 40mg, recently reduced to 20mg after "me" chasing my doctor regarding blood test results. After me asking if I needed to be on Artovastatin he checks results and says 'cholesterol is lower so we can drop the dose'... He'd been getting meto keep having blood tests as, apparently, I was showing signs of anemia/low iron as well as being 'pre' diabetic - no longer pre diabetic.
I'm of the opinion that the meds for my hiatus hernia, Omeprazole (or a derivative of), I've been taking for 25+ years has been effecting how my body takes up from food - hence low iron intake and now why I'm on Levothyroxine. Only on Levothyroxine after my own research on symptoms showing a possible cause of under active thyroid, mentioning this to my doctor and him checking to come back to me with "oh yes, your blood results do show a low thyroid count"...

Medication now prescribed being:
Artovastatin (side effects: tinnitus? Aches?)
Omeprazole (side effects possibility of restriction taking up essential vitamins etc., from food over the years?...
Tamsulosin (some side effects but unable to describe)
Levothyroxine (no side effects known/experienced)

Was prescribed Losarten for high BP, taken off because of effects of the Tamsulosin lowering BP. Later prescribed Amlodipine for high BP, side effects of dizziness - worse than previous - so taken off them. Now they "think", but haven't confirmed, I may have Postural Hypotension... waiting to hear from them after last blood test given on 1st July. Research of symptoms also shows my high blood pressure and 'Postural Hypotension' (dizziness) could be caused by under active thyroid... doctor is 'supposed' to monitor that the Levothyroxine dose is correct... So I'm probably going to have to attempt to make contact again.
 
Fortunately I get no side effects from my prescription drugs. :)

Atorvastatin
Aspirin
Metformin
Gliclazide
Linagliptin
Dapagliflozin
Levothyroxine
Omeprazole
Meloxicam
Allopurinol
Tamsulosin
Lisinopril
Amlopidine
Codeine
Pregabalin
Pioglitazone.
I've had very high blood pressure (and probably slightly high cholesterol) for years; despite not having quite hit 50 yet. Earlier in the year the GP put me on Atorvastatin and Lisinopril. I guess I've just been very lucky as the only "side effect" I've noticed is a significant drop in blood pressure (down to something considered healthy) - so I really can't complain.

I was advised to take them both last thing at night, as it may lessen side effects during waking hours. I don't know how significant that is, but in my scientific study of.... one... it's worked for me.
 
And my pharmacist advised me to take amlodipine and atorvastitine at different times of the day as this would reduce the very small but known incidence of them interacting with each other.
The doc who prescribed them didn't mention this, but as pharmacists tend to know what they're talking about, I take one last thing at night and the other in the morning...
 
I was advised to take them both last thing at night, as it may lessen side effects during waking hours. I don't know how significant that is, but in my scientific study of.... one... it's worked for me.
I changed surgeries after nearly 70 years, the new one is so much more eficcient that the one I left. The doctor went through the list and asked why I took the lisinopril and amlopidine at night - he said I should be taking them in the morning as it's in the daytime the b. p. needs to be kept down. I seem to remember being told to take the lisinopril at night went I first went on it years ago.
 

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