Personally I wouldn't use acrylic for a ZCI. It is very brittle and shatters on impact, so if anything goes wrong when you are sawing, you can easily end up with a destroyed throat plate. I don't see what advantage acrylic would have over a piece of plywood. MDF is OK but ply is better. Just make sure it is flat and not doing impressions of a poppadum.
I rough cut the plywood to the size I want, use DS tape to stick it to my original throat plate and flush-trim to size. There is a narrow gap between the TCT edges of the router cutter and the guide bearing and I have to make sure that the bearing is wholly on the steel whilst the cutter is wholly in the wood. 1mm either way and either it wont cut or the cutter gets ruined on the steel. If there is a bit of wood still to finish, I adjust the height of the bit, remove the steel and flush-trim the ply to itself.
The ply is a tad thinner than I need, so I mark on the underside where the supporting lugs are, drill pilot holes for small countersunk screws (but I don't fit them yet), which I will use to adjust the plate for level, but before trying it for size I drill a couple of 1" finger-holes, nicely rounded, so I can lift it out easily.
Once I'm happy with the fit, I move the fence right up to the throat, dead flush, replace the old throat plate,and cut a slot about 1/2 way along the ZCI. This is the area that will take the riving knife. Stop the saw, remove the workpiece and cut and fit a small sliver as a plug to close the back end, behind the RK. Fit and adjust the levelling screws. Install the new ZCI.
Lower the blade completely, move the fence up right next to the slot, wedge it in place if necessary, switch on and carefully raise the blade. Job done.
NB
If you later lower the blade, the ZCI is no longer strictly ZC. It will be ZC at the sides, but not at the front, directly in front of the teeth. That might matter if you are cutting MFC, for example.
ZCIs do wear, so it's worth making a batch rather than just one.