Assume an engine when running consumes all the oxygen in the air it ingests, and:
- 2.0 litre 4 cylinder engine
- idling speed 700 rpm
- gas exhausted per revolution = 1 litre (4 cycle engine)
- gas exhausted per hour = 4.2 cu m (700 rpm x 60 mins x 1 litre)
- assume volume of garage = 45 cu m (length 6m x width 3m x height 2.5m)
- assume volume of car interior = 5.4 cu m (length 3m x width 1.5m x height 1.2m)
If the percentage of oxygen in the air falls below 20% negative symptoms start to become apparent. Below 15% - acute hypoxia and serious risk of death.
To reduce the air in the car interior to ~15% would require the displacement of ~2cu m of air. It would take ~20-30 minutes. Somewhat imprecise as it depends on air mixing from the garage interior and outside - but likely to be low.
Bit more than a bad headache.