Torx, looking really good! Exciting stuff isn't it.
4x2 isn't overkill, it's quite a big building, and 4x2 on 400 centres is fairly standard... It's certainly the most common config for garden room structures.
Sips are stronger than you think, also they get more expensive the more customised they need to be, windows etc
If you can buy the standard size panels and stitch them together yourself without the need for a design service and a custom cutting service then cost is probably similar to traditional framing.
On roof pitch, the standard is 1 in 40, or it might be easier to think of it as 25mm drop for every metre of building depth.
Example, if you have a 3 metre deep building it will be 75mm taller at the front than the back. 4m deep building would be 100mm. 3.5m would be somewhere in between, 87.5mm. not sure if that helps
Martin