Macron won the French election out of nowhere, in an almost Trumpesque upset. He did so on the back of promises he has been unable to fulfil and is now deeply unpopular. Who is waiting in the wings, the likes of Marie Le Penn, right wing nationalists. They have made it very clear that they would seek to leave, so I wouldn't be so sure. Very sadly these sort of right wing politicians are gaining popularity in many countries, and many have similar anti EU views.
I really worry what will happen when Frau Merkel goes. She has been such a towering figure in European politics. Unfortunately she has already run into difficulties at home because of her liberal stance on immigration in particular. Now we have left Germany is by far the largest contributor to the EU, and the right wing there are very vocal in their opposition to what they are as Germany having to prop up other members. I have no idea who will replace Merkel, but it seems a fair bet that it will be someone less liberal than she has been.