I don't know about the costs, but I used to operate a small machine (as a teenager - holiday job). You will need:
- Probably three phase power,
- Compressed air
- An industrial oven or heating system for the pelletized stock (nylon in particular is very hygroscopic, which causes serious issues when operating the machines)
- Quite a bit of bench space: the bigger benchtop one we had used a horizontal piston.
The higher throughput units use a steam-heat/water-cooled cycle for the mould halves. There are a few consumables too, such as silicone release agent (might be the same as that used in GRP construction, not sure).
The moulds themselves wear out, particularly if there is any filler material, such as glass strands. If I was confident about the component design, and about a high quantity production run, I'd get two moulds made at the same time.
The injection pressure needed will vary with the mould design - you have to waste a fair bit of plastic in tweaking that and temperatures, to get good results, so I can understand the minimum quantity you got from the manufacturer (seems a bit low to me, actually).
If you switch colours or material, purging and cleaning the machine is noisy, time consuming and potentially rather dangerous. I'd guess you also need to keep it warm overnight.
Hope that informs, but it was state-of-the-art some decades ago!
E.