Thanks Steve, my concern was whether the 44x70's could happily support the bigger roof joists.
I'll go with 145 roof joists, double up on every other stud and double the headers. I'd rather over engineer and keep the roof up nice and sound.
I am planning to use it all year round - roof insulation:
A. 50mm PIR + 95mm air gap
B. 100mm PIR + 45mm air gap
C. 50mm PIR + 95mm rockwool
D. 100mm PIR + 45mm rockwool
E. None of the above/ something else?
On my garden cabin 4.5m x 4.2m I did 120mm celetex on roof, 50mm +50mm walls, 70mm floor.
I used 95x 45 for wall studwork, 50mm celetex in between, then 18mm Osb then 50mm outside, then 25mm battens, then cladding.
Inside I did 18mm moisture resistant mdf.
The 95x 45 with 50mm insulation allows electric cables to go in and if you put on 18mm board, it gives over 50mm from internal face to cables, so you don't have to worry about safe zones.
Also a 50mm space allows plenty of room for drilling the studs to run the cables.
I went for insulation levels that pretty much match building regs as I figured spending a few hundred quid up front would save heating costs. I have to say it's made a fantastic office, In the winter if I use it in the evening and heat it, when I go back in the morning, it's still retained some warmth. And it feels bone dry, never a hint of condensation, I have got A4 and A3 printers - the paper never gets damp.
I heat it with a fan heater for half an hour, then a oil filled rad, once it's reached say 18 deg, it needs little heat to maintain warmth.
I used tyvek house wrap externally and a 25mm air gap before cladding - that's vital for a dry structure