Your decision needs to be based on answers to questions on what you use it for and may use it for in the future.
Disk Size: Unless you use it for storing loads of large photo files and the like you probably don't need to worry about disk size. I find 250Gb more than enough to store my phone photos, office files etc. but I would wholeheartedly recommend a solid state disk (SSD) as they are far more reliable, silent and fast to boot up.
Screen and Graphics: Again this depends on what you like/need I have no need for high end graphics as I don't play games or use design software but I do like a quality screen.
Memory: Go for at least 16Gb to future proof the new computer
Network: Make sure it is 5Ghz dual band again to future proof it. The ability to run at 2.5 or 5 is dictated by your broadband router so a dual band will sort this.
CPU: This could nobble a computer so avoid low end CPU specs, likewise you probably don't need something that could give the Met Office forecasting system a run for its money. The better spec PC's will have more powerful CPUs. I tend to avoid AMD CPUs and plumb for Intel but that's just my view.
Everything else such as keyboard, screen size is very much down to personal choice so test it out if you can and carefully read several independent reviews for usage results. My wife has just moved from a 17" HP laptop to a 14" Acer Swift 3 with Intel Core i5 CPU, 1080 HD screen and 512Gb SSD and loves it - bough for just under £600. It is a very fast laptop with a superb screen.
Hope this helps but shout if something doesn't make sense