Simple answer= too much variables..and how much of it you are doing yourself?
just for foundation/shell/insulation/roof/windows/outside if you are doing EVERYTHING YOURSELF and just pay for materials you can do that for as little as 20-25k ,
than comes the expensive part= finishing the inside to a standard you want+ hooking up heat/water/communications .However again if you are smart you can cut your costs very very very well with this one,just depends what you want..all the furniture/stairs/windows In my house I have made myself so it really hasn't cost anything except materials.
I suggest building a Passive house (not with all the solar panel gimmicks but proper ones like they build them in Norway)
Well executed Plan will save you Massive amounts in the building process and after you start living in there.
You can do it for as little and as much as you want to spend...
Calculate your costs and than add another 30% to that = that's how much it will cost you
The small things which you didn't even thought about will end up costing you the most
I have built my own house where 95% of the labor has been only mine and the part you will hate the most is all the planing stuff and wasting all the money paying useless people who do nothing just to get a stamp.
I have no idea about labor costs, however they can be 2x of what your material costs are if you aren't the smartest guy on the block and get a bad deal, again = Depends!
However I guarantee that all the Fees + Labor costs will cost you way way more than the materials to build the house.
There is no online calculator to provide a simple/fast answer.
Start drawing up your plans and calculate yourself based on what you want, no1 can really answer this.